Ginger and its Effects on Inflammatory Diseases
DOI:
https://doi.org/10.17140/aftnsoj-1-117Keywords:
Ginger, Zingiber officinale, Inflammation, DiseasesAbstract
Today, Ginger is used as a spice all around the world. In the past, Ginger was con-sumed for the treatment of various diseases, including osteo-arthritis, neurological diseases, vomiting, asthma, and so on. It seems that Ginger can reduce inflammation in those diseases. We searched the following keywords in PubMed, Google scholar, and Scopus database until 2015: inflammation and Ginger, Ginger and diseases. Clinical trials, animal studies, and hu-man studies were included in the results of this search. Ginger extract with the antioxidant and anti-inflammatory ingredients such as 6 Gingerols, 6-Shogoals, Zhingerol, etc can reduce inflammatory mediators such as inflammatory cytokines and chemokines due to their effects on NF-κB activation, cyclooxygenase 2 reduction and serotonin receptors inhibition. It increases reducing antioxidant enzymes so it can be useful in inflammatory diseases improvement and their complications prevention. In conclusion, Ginger can help in the treatment of inflammatory chronic diseases such as Fatty Liver, Asthma, Cancer and Arthritis through anti-inflammatory, immunoregulatory and antioxidative mechanisms.
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