Treatment of Stage I Seminoma

Abstract

Stage I testicular seminoma is a curable condition. The primary treatment is high inguinal orchiectomy. The treatment options after surgery includes radiotherapy, chemotherapy with single agent carboplatin and active surveillance. Radiotherapy has evolved over the past decades with reduced treatment volume and radiation dose without compromising the outcome. Para aortic strip radiation 20 Gy in 10 fractions is equivalent to single agent carboplatin. Active surveillance is an acceptable approach for patients without adverse factors. There is no data comparing treatment versus active surveillance till date. This article reviews the evidences for each approach.